Prevalence of Amlodipine-induced Gingival Overgrowth
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Amlodipine- induced gingival overgrowth: a case report.
Drug-induced gingival overgrowth occurs in genetically susceptibIe individuals as a side effect of various drugs. There is a gross disfiguring enlargement of gingiva mostly in the anterior region leading to difficulty in mastication, speech and maintenance of oral hygiene. In this case report, amlodipine-induced gingival enlargement and its management are discussed. Drug substituion, appropriat...
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295 ABSTRACT: Gingival overgrowth (GO) is one of the most important clinical features of gingival pathology. Amlodipine is a comparatively new III generation calcium channels blocker, used for management of cardiovascular disorders. Although it is considered safe, it can also rarely induce GO. A case of severe amlodipine-induced GO, complicated by inflammatory changes due to plaque accumulation...
متن کاملAmlodipine induced gingival overgrowth: A case report
Introduction: Drug-induced gingival overgrowth (DIGO) remains a significant problem for the dental clinicians and the periodontologists. Patients medicated with certain drugs may be implicated in this unwanted side effect, which may interfere with esthetics, mastication or speech. Case Report: The case presented here is a 60-year-old female patient with drug induced gingival enlargement. Patien...
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Tacrolimus has been used successfully to prevent acute rejection of renal transplantation. It inhibits calcineurin, a Ca2+ calmodulindependent phosphatase, which results in reduced expression of interleukin-2 by T lymphocytes [17]. Tacrolimus has been associated with many side effects including nephrotoxicity, neurotoxicity and the induction of a diabetic state. Unlike cyclosporine A, studies t...
متن کاملAmlodipine-induced gingival overgrowth.
Amlodipine is a calcium channel blocker used in the management of angina and hypertension. We report 3 cases of gingival overgrowth in adult dentate patients associated with chronic usage of this drug. Gingival changes occurred within 3 months of dosage and appeared to be compounded by the patient's existing periodontal condition. In all 3 patients, there was sequestration of amlodipine in thei...
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